The complement system is central to first-line defense against invading pathogens. However, excessive complement activation and/or the loss of complement regulation contributes to the development of ...

It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...

The classical complement pathway is an important effector mechanism for clearance of infections, which is also employed in immunotherapies to eliminate tumor cells. Its initiation is governed by the ...

Your complement system consists of a group of important proteins in your bloodstream. These proteins help your immune system fight off harmful invaders, such as bacteria, and other foreign substances.

The complement system is a diverse set of proteins long known for its association with innate immunity. Recent decades have demonstrated novel location and roles for key complement proteins in the ...

Complement function should be evaluated in any patient with collagen-vascular disease, paroxysmal nocturnal hemoglobinuria, chronic nephritis, recurrent pyogenic infections, severe recurrent ...

Discover the latest articles and news in related subjects. Natural antibody and classical pathway complement also seem to be involved in contact sensitivity. In a complex model, involving natural ...

CMV, MHC-E, and the quest for an unconventional AIDS vaccine The complement system is an integral part of innate immune defense. It consists of about 50 proteins in plasma, on cell surfaces, and ...

The complement system is a biochemical cascade which helps clear pathogens from an organism. It is one part of the larger immune system. The complement system consists of a number of small proteins ...